Clinical variables |
Prolonged period of symptom duration |
Symmetric arthritis |
Hand arthritis |
Prolong duration of morning stiffness |
Larger number of swollen joints |
Larger number of painful joints |
Older age |
Female sex |
Laboratory variables |
Presence of HLADRß¹ |
IgG –RF positivity |
Anti-cyclic citrullinated protein positivity |
High level of C-reactive protein (CRP) |
High level of erythrocyte sedimentation rate (ESR) |
Imaging |
Bone erosion in plain radiographs |
Bone edema or erosion in MRI |
Domains | description | No | Score |
---|---|---|---|
Joint Involvement | Median-large joint§ | 1 | 0 |
2-10 | 1 | ||
Small joints ± | 1-3 | 2 | |
4-10 | 3 | ||
>10 ¥ | 5 | ||
Serology | No positive for either RF or anti-CCP At least one of these test positive at high titer* At least one of these test positive at low titer** | 0 | |
2 | |||
3 | |||
Duration of synovitis | +/> six weeks | 1 | |
Acute phase reactants | Neither CRP or ESR is abnormal Abnormal CRP or ESR | 0 | |
1 | |||
Patients receive highest point level they fulfill within each domain |